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@NaeemShahzad123 Create 2 separate, disconnected tables for your slicers where you have one column and a row per city name. You can then construct a measure that is essentially a Complex Selector like this: The Complex Selector - Microsoft Power BI Community. Specifically in your case something along the lines of:
Selector Measure =
VAR __City1 = SELECTEDVALUE('Slicer1'[Column])
VAR __City2 = SELECTEDVALUE('Slicer2'[Column])
VAR __RowCity = MAX('Table'[City Name])
VAR __Result = IF( __RowCity IN { __City1, __City2 }, 1, 0
RETURN
__Result
Then filter your visualization using the Filters pane and this measure set to 1.