@mattharling for the Edit in Desktop button do you have the August Release of Desktop for PBIRS Installed? Also the cache is a known issue that we fixed in this release however it does require to you do clear your cache one more time, it shouldn't happen in future releases. For any new issues you find please start new threads or post an issue on the issues forum:
@DaveW & @CB1 Can you start a new thread for the issues you are seeing, there were some dll version changes in this release that needed updated binding redirects. It will be easier to help if this is it's own thread.